Weight Loss after Gastric Bypass Surgery in Human Obesity Remodels Promoter Methylation

DNA methylation provides a mechanism by which environmental factors can control insulin sensitivity in obesity. Here, we assessed DNA methylation in skeletal muscle from obese people before and after Roux-en-Y gastric bypass (RYGB). Obesity was associated with altered expression of a subset of gene...

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Bibliographic Details
Main Authors: Romain Barres, Henriette Kirchner, Morten Rasmussen, Jie Yan, Francisc R. Kantor, Anna Krook, Erik Näslund, Juleen R. Zierath
Format: Article
Language:English
Published: Elsevier 2013-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713001253