Blockade of Autophagy Prevents the Development and Progression of Peritoneal Fibrosis

Blockade of Autophagy Prevents the Development and Progression of Peritoneal Fibrosis

Peritoneal fibrosis (PF) is a major cause of ultrafiltration failure in long-term peritoneal dialysis (PD) patients. Nevertheless, limited measures have been shown to be effective for the prevention and treatment of PF. Some views reveal that activation of autophagy ameliorates PF but others demonst...

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Bibliographic Details
Main Authors: Yingfeng Shi, Yan Hu, Yi Wang, Xiaoyan Ma, Lunxian Tang, Min Tao, Andong Qiu, Shougang Zhuang, Na Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Pharmacology
Subjects:
autophagy
peritoneal fibrosis
epithelial to mesenchymal transition
profibrotic signaling pathways
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.724141/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.724141/full

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