Use of genetically modified bacteria for drug delivery in humans: Revisiting the safety aspect

Abstract The use of live, genetically modified bacteria as delivery vehicles for biologics is of considerable interest scientifically and has attracted significant commercial investment. We have pioneered the use of the commensal gut bacterium Bacteroides ovatus for the oral delivery of therapeutics...

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Bibliographic Details
Main Authors: Udo Wegmann, Ana Lucia Carvalho, Martin Stocks, Simon R. Carding
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02591-6