Evidence of Müller Glia Conversion Into Retina Ganglion Cells Using Neurogenin2

Evidence of Müller Glia Conversion Into Retina Ganglion Cells Using Neurogenin2

Degenerative retinopathies are the leading causes of irreversible visual impairment in the elderly, affecting hundreds of millions of patients. Müller glia cells (MGC), the main type of glia found in the vertebrate retina, can resume proliferation in the rodent adult injured retina but contribute we...

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Bibliographic Details
Main Authors: Roberta Pereira de Melo Guimarães, Bruna Soares Landeira, Diego Marques Coelho, Daiane Cristina Ferreira Golbert, Mariana S. Silveira, Rafael Linden, Ricardo A. de Melo Reis, Marcos R. Costa
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
retina
müller glia cells
induced neurons
lineage-reprogramming
neurogenin2
Ascl1
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00410/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00410/full

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