Triple-Negative Essential Thrombocythemia: Clinical-Pathological and Molecular Features. A Single-Center Cohort Study

Triple-Negative Essential Thrombocythemia: Clinical-Pathological and Molecular Features. A Single-Center Cohort Study

Lack of demonstrable mutations affecting JAK2, CALR, or MPL driver genes within the spectrum of BCR-ABL1-negative myeloproliferative neoplasms (MPNs) is currently referred to as a triple-negative genotype, which is found in about 10% of patients with essential thrombocythemia (ET) and 5–10% of those...

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Main Authors: Daniele Cattaneo, Giorgio Alberto Croci, Cristina Bucelli, Silvia Tabano, Marta Giulia Cannone, Gabriella Gaudioso, Maria Chiara Barbanti, Kordelia Barbullushi, Paola Bianchi, Elisa Fermo, Sonia Fabris, Luca Baldini, Umberto Gianelli, Alessandra Iurlo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
essential thrombocytemia
triple-negative
bone marrow morphology
next-generation sequencing
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.637116/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.637116/full

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