Comparison of multi-lineage differentiation of hiPSCs reveals novel miRNAs that regulate lineage specification

Abstract MicroRNAs (miRNAs) are known to be crucial players in governing the differentiation of human induced pluripotent stem cells (hiPSCs). Despite their utter importance, identifying key lineage specifiers among the myriads of expressed miRNAs remains challenging. We believe that the current pra...

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Bibliographic Details
Main Authors: Lu Li, Kai-Kei Miu, Shen Gu, Hoi-Hung Cheung, Wai-Yee Chan
Format: Article
Language:English
Published: Nature Publishing Group 2018-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-27719-0