Small-intestinal TG2-specific plasma cells at different stages of coeliac disease

Small-intestinal TG2-specific plasma cells at different stages of coeliac disease

Abstract Background In coeliac disease, ingestion of gluten induces the production of transglutaminase 2 (TG2)-targeted autoantibodies by TG2-specific plasma cells present at high frequency in the small intestinal mucosa in untreated disease. During treatment with a gluten-free diet (GFD), the numbe...

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Bibliographic Details
Main Authors: Minna Hietikko, Outi Koskinen, Kalle Kurppa, Kaija Laurila, Päivi Saavalainen, Teea Salmi, Tuire Ilus, Heini Huhtala, Katri Kaukinen, Katri Lindfors
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Immunology
Subjects:
Coeliac disease
Gluten
Transglutaminase 2
Autoantibody
Small intestine
Online Access:http://link.springer.com/article/10.1186/s12865-018-0275-7

Internet

http://link.springer.com/article/10.1186/s12865-018-0275-7

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