A 3D printed mechanical bioreactor for investigating mechanobiology and soft tissue mechanics

Mechanical loading is an important cue for directing stem cell fate and engineered tissue formation in vitro. Stem cells cultured on 2-dimensional (D) substrates and in 3D scaffolds have been shown to differentiate toward bone, tendon, cartilage, ligament, and skeletal muscle lineages depending on t...

Full description

Bibliographic Details
Main Authors: Abigail R. Raveling, Sophia K. Theodossiou, Nathan R. Schiele
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:MethodsX
Online Access:http://www.sciencedirect.com/science/article/pii/S2215016118301298