Irradiated mesenchymal stem cells support stemness maintenance of hepatocellular carcinoma stem cells through Wnt/β-catenin signaling pathway

Abstract Background Cancer stem cells are the main reason of relapse, metastasis and resistance to anti-cancer therapies of Hepatocellular carcinoma (HCC). Mesenchymal stem cells (MSCs) are an important part of the tumor microenvironment. MSCs have been demonstrated to be involved in drug resistance...

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Bibliographic Details
Main Authors: Jing Hou, Naping Zhao, Pengxi Zhu, Jun Chang, Yan Du, Wei Shen
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Cell & Bioscience
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13578-020-00449-5