VIPER regulates naive T cell activation and effector responses: Implication in TLR4 associated acute stage T cell responses

Abstract Naive T cells are known to express the modest level of TLR4 while it is known to go down during TCR activation. However, information towards the requirement of TLR4 signaling during TCR or mitogenic activation of naive wild-type T cells remains scanty. Here we have investigated the endogeno...

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Bibliographic Details
Main Authors: Subhransu Sekhar Sahoo, Belluru M. Pratheek, Vikram S. Meena, Tapas Kumar Nayak, P. Sanjai Kumar, Saumya Bandyopadhyay, Prasanta Kumar Maiti, Subhasis Chattopadhyay
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25549-8