Revisiting the Role of Insulin-Like Growth Factor-I Receptor Stimulating Activity and the Apolipoprotein E in Alzheimer’s Disease

Revisiting the Role of Insulin-Like Growth Factor-I Receptor Stimulating Activity and the Apolipoprotein E in Alzheimer’s Disease

Background: Alterations in insulin-like growth factor I (IGF-I) signaling have been associated with dementia and Alzheimer’s disease (AD). Studies on the association between IGF-I levels and dementia risk have been inconclusive. We reported earlier that higher levels of IGF-I receptor stimulating ac...

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Bibliographic Details
Main Authors: Sara A. Galle, Ashley van der Spek, Madeleine L. Drent, Michael P. Brugts, Erik J. A. Scherder, Joseph A. M. J. L. Janssen, M. Arfan Ikram, Cornelia M. van Duijn
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
dementia
genetic epidemiology
insulin-like growth factor I
KIRA assay
apolipoprotein E
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00020/full

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https://www.frontiersin.org/article/10.3389/fnagi.2019.00020/full

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