Concurrent treatment with tamoxifen and CYP2D6 inibitors: clinical significance of drug interactions
Tamoxifen is used in the treatment of women with endocrine responsive breast cancer. It is a prodrug, which is metabolized by liver cytochrome P450 system (CYP) into metabolites with a potent anti-estrogenic activity; CYP2D6 is one of the most important enzymes involved in this metabolic pathw...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Slovenian Medical Association
2012-08-01
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| Series: | Zdravniški Vestnik |
| Online Access: | http://vestnik.szd.si/index.php/ZdravVest/article/view/593 |