Sema4A is implicated in the acceleration of Th17 cell-mediated neuroinflammation in the effector phase

Sema4A is implicated in the acceleration of Th17 cell-mediated neuroinflammation in the effector phase

Abstract Background Sema4A is a regulator of helper T cell (Th) activation and differentiation in the priming phase, which plays an important role in the pathogenesis of experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS). However, the role of Sema4A in the effector phase rem...

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Bibliographic Details
Main Authors: Toru Koda, Akiko Namba, Makoto Kinoshita, Yuji Nakatsuji, Tomoyuki Sugimoto, Kaori Sakakibara, Satoru Tada, Mikito Shimizu, Kazuya Yamashita, Kazushiro Takata, Teruyuki Ishikura, Syo Murata, Shohei Beppu, Atsushi Kumanogoh, Hideki Mochizuki, Tatsusada Okuno
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Journal of Neuroinflammation
Subjects:
Multiple sclerosis
Sema4A
Th17
Experimental autoimmune encephalomyelitis
Online Access:http://link.springer.com/article/10.1186/s12974-020-01757-w

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http://link.springer.com/article/10.1186/s12974-020-01757-w

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