Regional staging of white matter signal abnormalities in aging and Alzheimer's disease

White matter lesions, quantified as ‘white matter signal abnormalities’ (WMSA) on neuroimaging, are common incidental findings on brain images of older adults. This tissue damage is linked to cerebrovascular dysfunction and is associated with cognitive decline. The regional distribution of WMSA thro...

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Bibliographic Details
Main Authors: Emily R. Lindemer, Douglas N. Greve, Bruce R. Fischl, Jean C. Augustinack, David H. Salat
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:NeuroImage: Clinical
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158217300220