Mitochondrial Bioenergetics at the Onset of Drug Resistance in Hematological Malignancies: An Overview

Mitochondrial Bioenergetics at the Onset of Drug Resistance in Hematological Malignancies: An Overview

The combined derangements in mitochondria network, function and dynamics can affect metabolism and ATP production, redox homeostasis and apoptosis triggering, contributing to cancer development in many different complex ways. In hematological malignancies, there is a strong relationship between cell...

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Bibliographic Details
Main Authors: Alessandro Barbato, Grazia Scandura, Fabrizio Puglisi, Daniela Cambria, Enrico La Spina, Giuseppe Alberto Palumbo, Giacomo Lazzarino, Daniele Tibullo, Francesco Di Raimondo, Cesarina Giallongo, Alessandra Romano
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Oncology
Subjects:
OX-PHOS
mitochondria
multiple myeloma
acute myeloid leukemia
chronic lymphatic leukemia
lymphoma
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.604143/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.604143/full

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