Experimental Human Cell and Tissue Models of Pemphigus

Pemphigus is a chronic mucocutaneous autoimmune bullous disease that is characterized by loss of cell-cell contact in skin and/or mucous membranes. Past research has successfully identified desmosomes as immunological targets and has demonstrated that acantholysis is initiated through direct binding...

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Bibliographic Details
Main Authors: Gerda van der Wier, Hendri H. Pas, Marcel F. Jonkman
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Dermatology Research and Practice
Online Access:http://dx.doi.org/10.1155/2010/143871