Trypanocidal Action of (−)-Elatol Involves an Oxidative Stress Triggered by Mitochondria Dysfunction

Trypanocidal Action of (−)-Elatol Involves an Oxidative Stress Triggered by Mitochondria Dysfunction

Natural compounds have shown good potential for the discovery of new chemotherapeutics for the treatment of Chagas’ disease. Recently, our group reported the effective trypanocidal activity of (−)-elatol, extracted from the red macroalgae <em>Laurencia dendroidea</em> pre...

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Bibliographic Details
Main Authors: Benedito Prado Dias Filho, Sueli de Oliveira Silva, Celso Vataru Nakamura, Antonio Alonso, Tania Ueda-Nakamura, Vânia Cristina Desoti, Danielle Lazarin-Bidóia, Renato Crespo Pereira, Daniela Bueno Sudatti
Format: Article
Language:English
Published: MDPI AG 2012-08-01
Series:Marine Drugs
Subjects:
(−)-elatol
<em>Trypanosoma cruzi</em>
Chagas’ disease
mitochondria
oxidative stress
Online Access:http://www.mdpi.com/1660-3397/10/8/1631

Internet

http://www.mdpi.com/1660-3397/10/8/1631

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