Comparing DNA enrichment of proliferating cells following administration of different stable isotopes of heavy water

Abstract Deuterated water (2H2O) is a label commonly used for safe quantitative measurement of deuterium enrichment into DNA of proliferating cells. More recently, it has been used for labeling proteins and other biomolecules. Our in vitro - in vivo research reports important stable isotopic labelin...

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Bibliographic Details
Main Authors: Don E. Farthing, Nataliya P. Buxbaum, Philip J. Lucas, Natella Maglakelidze, Brittany Oliver, Jiun Wang, Kevin Hu, Ehydel Castro, Catherine V. Bare, Ronald E. Gress
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04404-2