Epithelial transport of immunogenic and toxic gliadin peptides in vitro.

Celiac disease is an autoimmune disorder caused by failure of oral tolerance against gluten in genetically predisposed individuals. The epithelial translocation of gluten-derived gliadin peptides is an important pathogenetic step; the underlying mechanisms, however, are poorly understood. Thus, we i...

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Bibliographic Details
Main Authors: Christian Zimmermann, Silvia Rudloff, Günter Lochnit, Sevgi Arampatzi, Wolfgang Maison, Klaus-Peter Zimmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4240668?pdf=render