On the performance of de novo pathway enrichment

Computational biology: Evaluation of network-based pathway enrichment tools De novo pathway enrichment methods are essential to understand disease complexity. They can uncover disease-specific functional modules by integrating molecular interaction networks with expression profiles. However, how sho...

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Bibliographic Details
Main Authors: Richa Batra, Nicolas Alcaraz, Kevin Gitzhofer, Josch Pauling, Henrik J. Ditzel, Marc Hellmuth, Jan Baumbach, Markus List
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-017-0007-2