Implication of 5-HT in the Dysregulation of Chloride Homeostasis in Prenatal Spinal Motoneurons from the G93A Mouse Model of Amyotrophic Lateral Sclerosis

Implication of 5-HT in the Dysregulation of Chloride Homeostasis in Prenatal Spinal Motoneurons from the G93A Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive motor neuron degeneration and muscle paralysis. The early presymptomatic onset of abnormal processes is indicative of cumulative defects that ultimately lead to a late manifestation of clinical symp...

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Bibliographic Details
Main Authors: Elodie Martin, William Cazenave, Anne-Emilie Allain, Daniel Cattaert, Pascal Branchereau
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
als
development
sod1<sup>g93a</sup> mouse
5-ht
chloride homeostasis
gaba/glycine
perforated patch-clamp
spinal cord
motoneuron
Online Access:https://www.mdpi.com/1422-0067/21/3/1107

Internet

https://www.mdpi.com/1422-0067/21/3/1107

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