Direct allylic C–H alkylation of enol silyl ethers enabled by photoredox–Brønsted base hybrid catalysis

Allylic C–H activation of enol silyl ethers via one-electron oxidation is usually accompanied by undesired desilylation. Here, under hybrid photoredox and Brønsted base catalysis, the authors show the mild functionalization of enol silyl ethers, providing a platform to access an array of complex car...

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Bibliographic Details
Main Authors: Kohsuke Ohmatsu, Tsubasa Nakashima, Makoto Sato, Takashi Ooi
Format: Article
Language:English
Published: Nature Publishing Group 2019-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10641-y