Epigenetic regulation of cell type-specific expression patterns in the human mammary epithelium.

Differentiation is an epigenetic program that involves the gradual loss of pluripotency and acquisition of cell type-specific features. Understanding these processes requires genome-wide analysis of epigenetic and gene expression profiles, which have been challenging in primary tissue samples due to...

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Bibliographic Details
Main Authors: Reo Maruyama, Sibgat Choudhury, Adam Kowalczyk, Marina Bessarabova, Bryan Beresford-Smith, Thomas Conway, Antony Kaspi, Zhenhua Wu, Tatiana Nikolskaya, Vanessa F Merino, Pang-Kuo Lo, X Shirley Liu, Yuri Nikolsky, Saraswati Sukumar, Izhak Haviv, Kornelia Polyak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3080862?pdf=render