Pharmacogenomics of Acetaminophen in Pediatric Populations: a Moving Target

Acetaminophen (APAP) is widely used as an over-the-counter fever reducer and pain reliever. However, the current therapeutic use of APAP is not optimal. The inter-patient variability in both efficacy and toxicity limits the use of this drug. This is particularly an issue in pediatric populations, wh...

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Bibliographic Details
Main Author: Wanqing eLiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00314/full