Pyrrolysyl-tRNA Synthetase, an Aminoacyl-tRNA Synthetase for Genetic Code Expansion

Genetic code expansion (GCE) has become a central topic of synthetic biology. GCE relies on engineered aminoacyl‐tRNA synthetases (aaRSs) and a cognate tRNA species to allow codon reassignment by co-translational insertion of non-canonical amino acids (ncAAs) into proteins. Introduction of such amin...

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Bibliographic Details
Main Authors: Ana Crnković, Tateki Suzuki, Dieter Söll, Noah M. Reynolds
Format: Article
Language:English
Published: Croatian Chemical Society 2016-06-01
Series:Croatica Chemica Acta
Online Access:http://hrcak.srce.hr/file/235773