Biotherapeutics: Challenges and Opportunities for Predictive Toxicology of Monoclonal Antibodies
Biotherapeutics are a rapidly growing portion of the total pharmaceutical market accounting for almost one-half of recent new drug approvals. A major portion of these approvals each year are monoclonal antibodies (mAbs). During development, non-clinical pharmacology and toxicology testing of mAbs di...
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Format: | Article |
Language: | English |
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MDPI AG
2018-11-01
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Series: | International Journal of Molecular Sciences |
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Online Access: | https://www.mdpi.com/1422-0067/19/11/3685 |