Transglutaminase-2 Mediates the Biomechanical Properties of the Colorectal Cancer Tissue Microenvironment that Contribute to Disease Progression

Transglutaminase-2 Mediates the Biomechanical Properties of the Colorectal Cancer Tissue Microenvironment that Contribute to Disease Progression

Colorectal cancer is the third most common cancer worldwide, and the fourth leading cause of malignancy-related mortality. This highlights the need to understand the processes driving this disease in order to develop new treatments and improve patient outcomes. A potential therapeutic target is the...

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Bibliographic Details
Main Authors: Robin Delaine-Smith, Nicola Wright, Chris Hanley, Rebecca Hanwell, Rahul Bhome, Marc Bullock, Cole Drifka, Kevin Eliceiri, Gareth Thomas, Martin Knight, Alex Mirnezami, Nicholas Peake
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cancers
Subjects:
colorectal
transglutaminase
remodelling
biomechanics
collagen
extracellular matrix
tumor microenvironment
Online Access:https://www.mdpi.com/2072-6694/11/5/701

Internet

https://www.mdpi.com/2072-6694/11/5/701

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