Interleukin-10 attenuates impairment of the blood-brain barrier in a severe acute pancreatitis rat model

Interleukin-10 attenuates impairment of the blood-brain barrier in a severe acute pancreatitis rat model

Abstract Background Impairment of the blood-brain barrier (BBB) in severe acute pancreatitis (SAP) could result in life-threatening pancreatic encephalopathy. Interleukin-10 (IL-10) is a classical cytokine that is well-known for its strong immunoregulatory and anti-inflammatory abilities. However, w...

Full description

Bibliographic Details
Main Authors: Ronggui Lin, Fei Chen, Shi Wen, Tianhong Teng, Yu Pan, Heguang Huang
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Journal of Inflammation
Subjects:
IL-10
Blood-brain barrier
Endothelial cell
Tight junction
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s12950-018-0180-0

Internet

http://link.springer.com/article/10.1186/s12950-018-0180-0

Similar Items