Transmembrane serine protease 2 Polymorphisms and Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Type 2 Infection: A German Case-Control Study

Transmembrane serine protease 2 Polymorphisms and Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Type 2 Infection: A German Case-Control Study

The transmembrane serine protease 2 (TMPRSS2) is the major host protease that enables entry of the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) into host cells by spike (S) protein priming. Single nucleotide polymorphisms (SNPs) in the gene TMPRSS2 have been associated with susc...

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Bibliographic Details
Main Authors: Kristina Schönfelder, Katharina Breuckmann, Carina Elsner, Ulf Dittmer, David Fistera, Frank Herbstreit, Joachim Risse, Karsten Schmidt, Sivagurunathan Sutharsan, Christian Taube, Karl-Heinz Jöckel, Winfried Siffert, Andreas Kribben, Birte Möhlendick
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Genetics
Subjects:
transmembrane serine protease 2
coronavirus disease 2019
severe acute respiratory syndrome coronavirus type 2
polymorphism
rs383510
rs2070788
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.667231/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.667231/full

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