Antibody-mediated disruption of the SARS-CoV-2 spike glycoprotein

Antibody-mediated disruption of the SARS-CoV-2 spike glycoprotein

Here, the authors characterise the binding and neutralisation properties of CR3022, a neutralising Ab isolated from a convalescent SARS patient, against SARS-CoV-2 spike trimers and show using Cryo-EM the disruption of SARS-CoV-2 spike by CR3022 Fab.

Bibliographic Details
Main Authors: Antoni G. Wrobel, Donald J. Benton, Saira Hussain, Ruth Harvey, Stephen R. Martin, Chloë Roustan, Peter B. Rosenthal, John J. Skehel, Steven J. Gamblin
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19146-5

Internet

https://doi.org/10.1038/s41467-020-19146-5

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