Atorvastatin Protects Myocardium Against Ischemia-Reperfusion Injury Through Inhibiting miR-199a-5p

Atorvastatin Protects Myocardium Against Ischemia-Reperfusion Injury Through Inhibiting miR-199a-5p

Objective: This study aimed to evaluate the protective effects of atorvastatin against myocardial ischemia/reperfusion (I/R) injury in cardiomyocytes and its possible underlying mechanism. Method: Direct cytotoxic effect of OGD/R on cardiomyocytes with and without atorvastatin pretreatment was evalu...

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Bibliographic Details
Main Authors: YaBei Zuo, YuZhao Wang, HaiJuan Hu, Wei Cui
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Glycogen synthase kinase-3β (GSK-3β)
Ischemia-reperfusion injury
microRNA
miR-199a-5p
Atorvastatin
Online Access:http://www.karger.com/Article/FullText/447809

Internet

http://www.karger.com/Article/FullText/447809

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