Unique and Common Features of Innate-Like Human Vδ2+ γδT Cells and Mucosal-Associated Invariant T Cells

Unique and Common Features of Innate-Like Human Vδ2+ γδT Cells and Mucosal-Associated Invariant T Cells

Mucosal-associated invariant T (MAIT) cells are innate-like T cells abundant in humans that can be activated in a TCR-independent manner by inflammatory and antiviral cytokines. In humans, the capacity for TCR-independent activation is functionally linked to a transcriptional program that can be ide...

Full description

Bibliographic Details
Main Authors: Nicholas M. Provine, Benedikt Binder, Michael E. B. FitzPatrick, Anita Schuch, Lucy C. Garner, Kate D. Williamson, Bonnie van Wilgenburg, Robert Thimme, Paul Klenerman, Maike Hofmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
mucosal-associated invariant T
γδ T cells
innate-like T cells
hepatitis C virus
mucosal immunology
Vδ2 γδ T cells
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00756/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00756/full

Similar Items