KLF4-Induced Connexin40 Expression Contributes to Arterial Endothelial Quiescence

KLF4-Induced Connexin40 Expression Contributes to Arterial Endothelial Quiescence

Shear stress, a blood flow-induced frictional force, is essential in the control of endothelial cell (EC) homeostasis. High laminar shear stress (HLSS), as observed in straight parts of arteries, assures a quiescent non-activated endothelium through the induction of Krüppel-like transcription factor...

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Bibliographic Details
Main Authors: Jean-François Denis, Mannekomba R. Diagbouga, Filippo Molica, Aurélie Hautefort, Tanja Linnerz, Masakatsu Watanabe, Sylvain Lemeille, Julien Y. Bertrand, Brenda R. Kwak
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Physiology
Subjects:
endothelium
shear stress
KLF4
Cx40
cell proliferation
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00080/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.00080/full

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