Embracing Mechanobiology in Next Generation Organ-On-A-Chip Models of Bone Metastasis

Bone metastasis in breast cancer is associated with high mortality. Biomechanical cues presented by the extracellular matrix play a vital role in driving cancer metastasis. The lack of in vitro models that recapitulate the mechanical aspects of the in vivo microenvironment hinders the development of...

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Bibliographic Details
Main Authors: Ellen E. Slay, Fiona C. Meldrum, Virginia Pensabene, Mahetab H. Amer
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Medical Technology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmedt.2021.722501/full