Dynamic instability of genomic methylation patterns in pluripotent stem cells

<p>Abstract</p> <p>Background</p> <p>Genomic methylation patterns are established during gametogenesis, and perpetuated in somatic cells by faithful maintenance methylation. There have been previous indications that genomic methylation patterns may be less stable in emb...

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Bibliographic Details
Main Authors: Ooi Steen KT, Wolf Daniel, Hartung Odelya, Agarwal Suneet, Daley George Q, Goff Stephen P, Bestor Timothy H
Format: Article
Language:English
Published: BMC 2010-09-01
Series:Epigenetics & Chromatin
Online Access:http://www.epigeneticsandchromatin.com/content/3/1/17