Detection of <i>CTNNB1</i> Hotspot Mutations in Cell-Free DNA from the Urine of Hepatocellular Carcinoma Patients

Detection of <i>CTNNB1</i> Hotspot Mutations in Cell-Free DNA from the Urine of Hepatocellular Carcinoma Patients

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide. The beta-catenin gene, <i>CTNNB1,</i> is among the most frequently mutated in HCC tissues. However, mutational analysis of HCC tumors is hampered by the difficulty of obtaining tissue samples using trad...

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Bibliographic Details
Main Authors: Selena Y. Lin, Ting-Tsung Chang, Jamin D. Steffen, Sitong Chen, Surbhi Jain, Wei Song, Yih-Jyh Lin, Ying-Hsiu Su
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Diagnostics
Subjects:
hepatocellular carcinoma
cell-free DNA
beta-catenin
urine
mutation
recurrence
Online Access:https://www.mdpi.com/2075-4418/11/8/1475

Internet

https://www.mdpi.com/2075-4418/11/8/1475

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