Detection of <i>CTNNB1</i> Hotspot Mutations in Cell-Free DNA from the Urine of Hepatocellular Carcinoma Patients

Detection of <i>CTNNB1</i> Hotspot Mutations in Cell-Free DNA from the Urine of Hepatocellular Carcinoma Patients

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide. The beta-catenin gene, <i>CTNNB1,</i> is among the most frequently mutated in HCC tissues. However, mutational analysis of HCC tumors is hampered by the difficulty of obtaining tissue samples using trad...

Full description

Bibliographic Details
Main Authors: Selena Y. Lin, Ting-Tsung Chang, Jamin D. Steffen, Sitong Chen, Surbhi Jain, Wei Song, Yih-Jyh Lin, Ying-Hsiu Su
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Diagnostics
Subjects:
hepatocellular carcinoma
cell-free DNA
beta-catenin
urine
mutation
recurrence
Online Access:https://www.mdpi.com/2075-4418/11/8/1475

Similar Items

Similar Items