Antifungal Activity of the Biphosphinic Cyclopalladate C7a against Candida albicans Yeast Forms In Vitro and In Vivo

Antifungal Activity of the Biphosphinic Cyclopalladate C7a against Candida albicans Yeast Forms In Vitro and In Vivo

Vulvovaginal and invasive candidiasis are frequent conditions in immunosuppressed individuals caused by Candida albicans and non-albicans Candida spp. Fluconazole and Amphotericin B are the main drugs used to fight the infection. However, resistance to fluconazole and other azole antifungal drugs is...

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Bibliographic Details
Main Authors: Julian E. Muñoz, Diego C. P. Rossi, Kelly Ishida, Cristina C. Spadari, Marcia S. C. Melhem, Daniel M. Garcia, Antonio C. F. Caires, Carlos P. Taborda, Elaine G. Rodrigues
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Microbiology
Subjects:
Candida spp.
clinical isolates
antifungal chemotherapy
cyclopalladated C7a
vaginal candidiasis
disseminated candidiasis
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.00771/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.00771/full

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