Tetrathiomolybdate sensitizes ovarian cancer cells to anticancer drugs doxorubicin, fenretinide, 5-fluorouracil and mitomycin C

Tetrathiomolybdate sensitizes ovarian cancer cells to anticancer drugs doxorubicin, fenretinide, 5-fluorouracil and mitomycin C

<p>Abstract</p> <p>Background</p> <p>Our recent study showed that tetrathiomolybdate (TM), a drug to treat copper overload disorders, can sensitize drug-resistant endometrial cancer cells to reactive oxygen species (ROS)-generating anticancer drug doxorubicin. To expand...

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Bibliographic Details
Main Authors: Kim Kyu Kwang, Lange Thilo S, Singh Rakesh K, Brard Laurent, Moore Richard G
Format: Article
Language:English
Published: BMC 2012-04-01
Series:BMC Cancer
Subjects:
Tetrathiomolybdate
Combination treatment
Doxorubicin
Mitomycin C
Fenretinide
5-fluorouracil
ROS generation
Online Access:http://www.biomedcentral.com/1471-2407/12/147

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http://www.biomedcentral.com/1471-2407/12/147

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