Novel Osteogenic Behaviors around Hydrophilic and Radical-Free 4-META/MMA-TBB: Implications of an Osseointegrating Bone Cement

Novel Osteogenic Behaviors around Hydrophilic and Radical-Free 4-META/MMA-TBB: Implications of an Osseointegrating Bone Cement

Poly(methyl methacrylate) (PMMA)-based bone cement, which is widely used to affix orthopedic metallic implants, is considered bio-tolerant but lacks osteoconductivity and is cytotoxic. Implant loosening and toxic complications are significant and recognized problems. Here we devised two strategies t...

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Bibliographic Details
Main Authors: Yoshihiko Sugita, Takahisa Okubo, Makiko Saita, Manabu Ishijima, Yasuyoshi Torii, Miyuki Tanaka, Chika Iwasaki, Takeo Sekiya, Masako Tabuchi, Naser Mohammadzadeh Rezaei, Takashi Taniyama, Nobuaki Sato, Juri Saruta, Masakazu Hasegawa, Makoto Hirota, Wonhee Park, Masaichi Chang-Il Lee, Hatsuhiko Maeda, Takahiro Ogawa
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:International Journal of Molecular Sciences
Subjects:
arthroplasty
total hip replacement
free radical
PMMA
cytotoxicity
implants
Online Access:https://www.mdpi.com/1422-0067/21/7/2405

Internet

https://www.mdpi.com/1422-0067/21/7/2405

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