Description of the genetic variants identified in a cohort of patients diagnosed with localized anal squamous cell carcinoma and treated with panitumumab

Description of the genetic variants identified in a cohort of patients diagnosed with localized anal squamous cell carcinoma and treated with panitumumab

Abstract Squamous cell carcinoma is the most frequent histologic type of anal carcinoma. The standard of care since the 1970s has been a combination of 5-fluorouracil, mitomycin C, and radiotherapy. This treatment is very effective in T1/T2 tumors (achieving complete regression in 80–90% of tumors)....

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Bibliographic Details
Main Authors: Lucía Trilla-Fuertes, Angelo Gámez-Pozo, Joan Maurel, Rocio Garcia-Carbonero, Jaume Capdevila, Laura G-Pastrián, Marta Mendiola, Cristina Peña, Rocío López-Vacas, Miriam Cuatrecasas, Pilar García-Alfonso, Ricardo Ramos-Ruiz, Carlos Llorens, Ismael Ghanem, Carles Conill, Victoria Heredia-Soto, Ángel Campos-Barros, Juan Ángel Fresno Vara, Jaime Feliu
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86966-w

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https://doi.org/10.1038/s41598-021-86966-w

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