General anesthetic conditions induce network synchrony and disrupt sensory processing in the cortex

General anesthetic conditions induce network synchrony and disrupt sensory processing in the cortex

General anesthetics are commonly used in animal models to study how sensory signals are represented in the brain. Here, we used two-photon (2P) calcium activity imaging with cellular resolution to investigate how neuronal activity in layer 2/3 of the mouse barrel cortex is modified under the influen...

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Bibliographic Details
Main Authors: Thomas eLissek, Horst A Obenhaus, Desiree eDitzel, Takeharu eNagai, Atsushi eMiyawaki, Rolf eSprengel, Mazahir T Hasan
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Anesthetics
Cerebral Cortex
Isoflurane
genetically encoded calcium indicators
two-photon imaging
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00064/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00064/full

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