Lentivirus expressing shRNAs inhibit the replication of contagious ecthyma virus by targeting DNA polymerase gene

Lentivirus expressing shRNAs inhibit the replication of contagious ecthyma virus by targeting DNA polymerase gene

Abstract Background Contagious ecthyma or Orf is known as a zoonotic disease remains prevalently worldwide despite the application of some control strategies against it. RNAi particularly shRNA provides us with the chance to tackle this obstacle by an encouraging new approach. The current study indi...

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Bibliographic Details
Main Authors: Leila Asadi Samani, Behnaz Saffar, Azam Mokhtari, Ehsan Arefian
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Biotechnology
Subjects:
ORFV
Lentiviral plasmid
DNA polymerase
RNAi
TCID50
Real-time PCR
Online Access:http://link.springer.com/article/10.1186/s12896-020-00611-4

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http://link.springer.com/article/10.1186/s12896-020-00611-4

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