Secreted midbody remnants are a class of extracellular vesicles molecularly distinct from exosomes and microparticles

Rai et al. characterise the properties of secreted midbody remnants, showing they are distinct from exosomes and microvesicles. The authors also find that these vesicles are engulfed by cells and promote anchorage independent growth and invasive phenotypes in NIH3T3 fibroblasts.

Bibliographic Details
Main Authors: Alin Rai, David W. Greening, Rong Xu, Maoshan Chen, Wittaya Suwakulsiri, Richard J. Simpson
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01882-z