The Role of the Kappa Opioid System in Comorbid Pain and Psychiatric Disorders: Function and Implications

The Role of the Kappa Opioid System in Comorbid Pain and Psychiatric Disorders: Function and Implications

Both pain and psychiatric disorders, such as anxiety and depression, significantly impact quality of life for the sufferer. The two also share a strong pathological link: chronic pain-induced negative affect drives vulnerability to psychiatric disorders, while patients with comorbid psychiatric diso...

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Bibliographic Details
Main Authors: Miao-Jin Ji, Jiao Yang, Zhi-Qiang Gao, Liang Zhang, Chao Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Neuroscience
Subjects:
kappa opioid system
pain-induced negative affect
cormorbid pain and psychiatric disorders
KOR agonists
KOR antagonists
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.642493/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2021.642493/full

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