Tropism of mesenchymal stem cell toward CD133+ stem cell of glioblastoma in vitro and promote tumor proliferation in vivo

Abstract Background Previous studies have demonstrated remarkable tropism of mesenchymal stem cells (MSCs) toward malignant gliomas, making these cells a potential vehicle for delivery of therapeutic agents to disseminated glioblastoma (GBM) cells. However, the potential contribution of MSCs to tumo...

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Bibliographic Details
Main Authors: Lorena Favaro Pavon, Tatiana Tais Sibov, Andrea Vieira de Souza, Edgar Ferreira da Cruz, Suzana M. F. Malheiros, Francisco Romero Cabral, Jean Gabriel de Souza, Pamela Boufleur, Daniela Mara de Oliveira, Silvia Regina Caminada de Toledo, Luciana C. Marti, Jackeline Moraes Malheiros, Fernando F. Paiva, Alberto Tannús, Sérgio Mascarenhas de Oliveira, Ana Marisa Chudzinski-Tavassi, Manoel A. de Paiva Neto, Sérgio Cavalheiro
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-018-1049-0