Dihydromyricetin Enhances the Chemo-Sensitivity of Nedaplatin via Regulation of the p53/Bcl-2 Pathway in Hepatocellular Carcinoma Cells.

Chemotherapy is an effective weapon in the battle against cancer. Nedaplatin (NDP) is an improved platinum-containing drug with lower cytotoxicity than other similar drugs. However, the repeated use of NDP results in substantial hepatocyte damage as well as drug resistance in hepatocellular carcinom...

Full description

Bibliographic Details
Main Authors: Lianggui Jiang, Qingyu Zhang, Hao Ren, Sheng Ma, CaiJie Lu, Bin Liu, Jie Liu, Jian Liang, Mingyi Li, Runzhi Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4411137?pdf=render