RPA and Rad51 constitute a cell intrinsic mechanism to protect the cytosol from self DNA
A central antiviral defence is immune recognition of cystolic DNA. Here the authors show that RPA and RAD51, in cooperation with TREX1, function to protect the cytosol from self-DNA.
Main Authors: | , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-05-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms11752 |