Tussilagone Suppresses Angiogenesis by Inhibiting the VEGFR2 Signaling Pathway

Tussilagone Suppresses Angiogenesis by Inhibiting the VEGFR2 Signaling Pathway

Tussilagone (TSL) is a sesquiterpenoid isolated from Tussilago farfara, which has been used as a traditional medicine for the treatment of asthma and bronchitis. It also takes part in the anti-inflammatory and antioxidant effects, but its role in angiogenesis is unknown. Angiogenesis is a cancer fea...

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Bibliographic Details
Main Authors: Jia Li, Jiangtong Peng, Shengnan Zhao, Yi Zhong, Yilong Wang, Ji Hu, Chao Zhang, Min Cheng, Geqing Xia, Yu Hu, Kai Huang, Yan Wang, Minglu Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Pharmacology
Subjects:
angiogenesis
TUSSILAGONE
VEGFR2 signaling pathway
human umbilical vascular endothelial cell
vascular endothelial growth factor
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00764/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00764/full

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