TBX21 and HLX1 polymorphisms influence cytokine secretion at birth.

TBX21 and HLX1 polymorphisms influence cytokine secretion at birth.

TBX21 (T cell specific T-box transcription factor) and HLX1 (H.20-like homeobox 1) are crucial transcription factors of T(H)1-cells, inducing their differentiation and suppressing T(H)2 commitment, particularly important for early life immune development. This study investigated the influence of TBX...

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Bibliographic Details
Main Authors: Vera Isabel Casaca, Sabina Illi, Kathrin Suttner, Isolde Schleich, Nikolaus Ballenberger, Elizabeth Klucker, Elif Turan, Erika von Mutius, Michael Kabesch, Bianca Schaub
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3268767?pdf=render

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http://europepmc.org/articles/PMC3268767?pdf=render

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